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While classical physics is consistent with an objectivist point of view, the advent of modern physics undermines its fundamental assumptions. Quantum mechanics, in particular, put a question to the philosophy of science as to whether its intrinsically probabilistic interpretation should be revised in order to save the traditional epistemology, or should be adopted unconditionally, along with its revolutionary consequences. We propose some crucial arguments in favour of the second option. Finally, we discuss how the above choice may suggest a constructivist view about the nature of physical sciences.