LA RIVOLUZIONE DELLA CRIO-MICROSCOPIA ELETTRONICA NELLO STUDIO STRUTTURALE DI PROTEINE E ACIDI NUCLEICI

https://doi.org/10.4081/scie.2017.638

Autori

Abstract

Observing the fine details of molecular structures (e.g. in proteins and in nucleic acids) has been a central part of Structural Biology over the past 50 years. The recent advent of single particle cryo-electron microscopy brought a revolution in this field, that previously relied on X-ray crystallography and nuclear magnetic resonance. It is now possible to explore the structures of large subcellular assemblies, such as the ribosome, resolving details on the scale of amino acids and nucleotides, in favorable cases reaching the 2 Ã… resolution level.

Dimensions

Altmetric

PlumX Metrics

Downloads

I dati di download non sono ancora disponibili.

##submission.downloads##

Pubblicato
2020-03-26
Statistiche
  • Abstract views: 402

  • pdf: 358
Come citare
Bolognesi, M. (2020). LA RIVOLUZIONE DELLA CRIO-MICROSCOPIA ELETTRONICA NELLO STUDIO STRUTTURALE DI PROTEINE E ACIDI NUCLEICI. Istituto Lombardo - Accademia Di Scienze E Lettere - Rendiconti Di Scienze. https://doi.org/10.4081/scie.2017.638